RASSF10 Antikörper (N-Term)

Produktnummer ABIN783486

Produktdetails anti-RASSF10 Antikörper

Target: RASSF10 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 10 (RASSF10))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASSF10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects RASSF10 at N-term. RASSF10 antibody will not cross-react with other RAS association domain-containing family members.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the amino terminus of human RASSF10

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Referenzen für anti-RASSF10 Antikörper (ABIN783486)

Sherwood, Manbodh, Sheppard, Chalmers: "RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis." in: Molecular biology of the cell, Vol. 19, Issue 4, pp. 1772-82, (2008) (PubMed).

Details zu RASSF10

Target: RASSF10 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 10 (RASSF10))

Andere Bezeichnung: RASSF10 (RASSF10 Produkte)

Synonyme: 4632411J06Rik antikoerper, Ras association domain family member 10 antikoerper, Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 antikoerper, RASSF10 antikoerper, Rassf10 antikoerper

Hintergrund: RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.Synonyms: Ras association domain-containing protein 10

Gen-ID: 644943

NCBI Accession: NP_001073990

UniProt: A6NK89