KAL1 Antikörper (Center)

Produktnummer ABIN783480

Der Kaninchen Polyklonal anti-KAL1 Antikörper (ABIN783480) detektiert spezifisch KAL1 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KAL1 Antikörper (Center) (ABIN783480)

Target: KAL1 (Kallmann Syndrome 1 Sequence (KAL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-KAL1 Antikörper

Bindungsspezifität: Center

Spezifität: This antibody detects Anosmin (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Affinity chromatography

Immunogen: Raised against an 18 amino acid peptide near the center of human Anosmin

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu KAL1

Target: KAL1 (Kallmann Syndrome 1 Sequence (KAL1))

Andere Bezeichnung: Anosmin-1

Hintergrund: Mutations in Anosmin-1, an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.Synonyms: ADMLX, Adhesion molecule-like X-linked, KAL, KAL1, KALIG1, Kallmann syndrome protein

Gen-ID: 3730

NCBI Accession: NP_000207

UniProt: P23352