Der Kaninchen Polyklonal anti-SLAMF1 Antikörper (ABIN783432) detektiert spezifisch SLAMF1 in WB und EIA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
This antibody detects CD150 / SLAMF1 at N-term. Two isoforms of SLAMF1 are known to exist, this antibody will recognize both isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
15 amino acid peptide near the amino terminus of human SLAMF1
SLAMF1
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
SLAM-4
APC
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target
SLAMF1
(Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
Andere Bezeichnung
CD150 / SLAMF1
Hintergrund
The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).Synonyms: CDw150, Ipo-3, Signaling lymphocytic activation molecule, Slam