This antibody detects CD150 / SLAMF1 at N-term. Two isoforms of SLAMF1 are known to exist, this antibody will recognize both isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
15 amino acid peptide near the amino terminus of human SLAMF1
CD150 antikoerper, SLAM antikoerper, SLAMF1 antikoerper, 4933415F16 antikoerper, AA177906 antikoerper, CDw150 antikoerper, ESTM51 antikoerper, IPO-3 antikoerper, Slam antikoerper, RGD1560634 antikoerper, signaling lymphocytic activation molecule family member 1 antikoerper, SLAMF1 antikoerper, Slamf1 antikoerper
Hintergrund
The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).Synonyms: CDw150, Ipo-3, Signaling lymphocytic activation molecule, Slam