TM4SF1 Antikörper (N-Term)

Produktnummer ABIN783425

Der Kaninchen Polyklonal anti-TM4SF1 Antikörper wird verwendet zum Nachweis von TM4SF1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und EIA.

Kurzübersicht für TM4SF1 Antikörper (N-Term) (ABIN783425)

Target: TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TM4SF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-TM4SF1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects TM4SF1 at N-term. At least three isoforms of TM4SF1 are known to exist, this antibody will recognize only the two largest isoforms. TM4SF1 antibody is predicted to not cross-react with other tetraspanin proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the amino terminus of human TM4SF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu TM4SF1

Target: TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))

Andere Bezeichnung: TM4SF1

Hintergrund: TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.Synonyms: M3S1, Membrane component surface marker 1, TAAL6, Transmembrane 4 L6 family member 1, Tumor-associated antigen L6

Gen-ID: 4071

NCBI Accession: NP_055035

UniProt: P30408