MYZAP Antikörper (C-Term)

Produktnummer ABIN783419

Der Kaninchen Polyklonal anti-MYZAP Antikörper wird verwendet zum Nachweis von MYZAP in Proben von Human, Maus und Ratte. Er wurde validiert für WB und EIA.

Kurzübersicht für MYZAP Antikörper (C-Term) (ABIN783419)

Target: MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYZAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-MYZAP Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects MYOZAP at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the carboxy terminus of human MYOZAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu MYZAP

Target: MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

Andere Bezeichnung: MYOZAP

Hintergrund: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein . It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.Synonyms: GCOM1, GRINL1A, Gup, Gup1, Myocardium-enriched zonula occludens-1-interacting protein, glutamate receptor ionotropic N-methyl D-aspartate-like 1A

Gen-ID: 145781

NCBI Accession: NP_001018100

UniProt: P0CAP1