ESRP1 Antikörper (N-Term)

Produktnummer ABIN783405

Dieser Anti-ESRP1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ESRP1 in WB, IHC (p), IF und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ESRP1 Antikörper (N-Term) (ABIN783405)

Target: ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-ESRP1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects ESRP1 / RBM35A at N-term. It is predicted to not cross-react with other RBM35/ESRP family members. At least five isoforms of RBM35A are known to exist, this antibody will detect all five.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity Chromatography purified via peptide column

Immunogen: 12 amino acid peptide near the amino terminus of Human RBM35A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ESRP1

Target: ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))

Andere Bezeichnung: ESRP1 / RBM35A

Hintergrund: RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.Synonyms: Epithelial splicing regulatory protein 1, RNA-binding motif protein 35A, RNA-binding protein 35A

Gen-ID: 54845

NCBI Accession: NP_001030087

UniProt: Q6NXG1