This antibody detects OGFOD2 at Center. OGFOD2 antibody is predicted to not cross-react with other TPA1 protein family members. At least three isoforms are known to exist, this antibody will only detect the two larger isoforms.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
17 amino acid peptide near the center of human OGFOD2
OGFOD2
Reaktivität: Ratte
WB, FACS, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 680
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target
OGFOD2
(2-Oxoglutarate and Iron-Dependent Oxygenase Domain Containing 2 (OGFOD2))
Andere Bezeichnung
OGFOD2
Hintergrund
OGFOD2 is a member of the 2-OG-Fe(II) dioxygenase family which plays an important role in ischemic survival and stress. Like the related protein OGFOD1, OGFOD2 is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. Little is known about the function of OGFOD2, but its similarity to OGFOD1 suggests that it is a novel stress granule component that may play an important proapoptotic role in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.Synonyms: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2, FLJ13491