OGFOD1 Antikörper (C-Term)
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- Target Alle OGFOD1 Produkte
- OGFOD1 (2-Oxoglutarate and Iron-Dependent Oxygenase Domain Containing 1 (OGFOD1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser OGFOD1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects OGFOD1 at C-term. OGFOD1 antibody is predicted to not cross-react with other TPA1 protein family members. At least two isoforms are known to exist, this antibody will only detect the larger isform.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 18 amino acid peptide near the carboxy terminus of human OGFOD1
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Target
- OGFOD1 (2-Oxoglutarate and Iron-Dependent Oxygenase Domain Containing 1 (OGFOD1))
- Andere Bezeichnung
- OGFOD1 (OGFOD1 Produkte)
- Hintergrund
- OGFOD1, a member of the 2-OG-Fe(II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.Synonyms: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, FLJ10826, KIAA1612, TPA1, Termination and polyadenylation 1 homolog
- Gen-ID
- 55239
- NCBI Accession
- NP_060703
- UniProt
- Q8N543
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