LRRTM2 Antikörper (C-Term)

Produktnummer ABIN783381

Dieser Anti-LRRTM2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von LRRTM2 in WB und EIA. Geeignet für Human, Ratte und Maus.

Kurzübersicht für LRRTM2 Antikörper (C-Term) (ABIN783381)

Target: LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRTM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-LRRTM2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects LRRTM2 at C-term. LRRTM2 antibody is predicted to not cross-react with other LRRTM family members.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human LRRTM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu LRRTM2

Target: LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))

Andere Bezeichnung: LRRTM2

Hintergrund: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development.Synonyms: KIAA0416, LRRN2, Leucine-rich repeat neuronal 2 protein, Leucine-rich repeat transmembrane neuronal protein 2

Gen-ID: 26045

NCBI Accession: NP_056379

UniProt: O43300

Pathways: Synaptic Membrane