ZBTB7A Antikörper (N-Term)

Produktnummer ABIN783361

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ZBTB7A in WB, IHC (p), IF und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für ZBTB7A Antikörper (N-Term) (ABIN783361)

Target: ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-ZBTB7A Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects ZBTB7A at N-term. At least two isoforms of ZBTB7A are known to exist, this antibody will recognize both isoforms. This antibody is predicted not to cross-react with other ZBTB protein family members.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity Chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the amino terminus of Human ZBTB7A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ZBTB7A

Target: ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

Andere Bezeichnung: ZBTB7A / Pokemon

Hintergrund: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB7A, also known as LRF, was initially identified as a potential target of the LAZ-3/BCL-6 oncogene. Later reports demonstrated that it could bind to the wild-type IST (inducer of short transcripts) elements of HIV-1 long terminal repeats (LTRs) and stimulate Tat activity on the HIV-1 LTR. More recently it ZBTB7A has been recognized as a proto-oncogene whose overexpression contributes to malignancy in breast cancer and functions as a co-repressor of the androgen receptor in prostate cancer cells.Synonyms: FBI-1, FBI1, Factor binding IST protein 1, LRF, Leukemia/lymphoma-related factor, POK (POZ and Krueppel) erythroid myeloid ontogenic factor, TIP21, TTF-I-interacting peptide 21, ZBTB7, Zinc finger and BTB domain-containing protein 7A

Gen-ID: 51341

NCBI Accession: NP_056982

UniProt: O95365