Aggrecan Antikörper (N-Term)
Kurzübersicht für Aggrecan Antikörper (N-Term) (ABIN782461)
Target
Alle Aggrecan (ACAN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
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Immunogen
- Synthetic peptide (- KLH conjugated) corresponding to N-terminal domain of Human Aggrecan.
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Isotyp
- IgG
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anti-Aggrecan (ACAN) (AA 34-147) antibody
ACAN Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Aggrecan (ACAN) (AA 34-147) antibodyACAN Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Aggrecan (ACAN) (AA 56-155) antibodyACAN Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2A8 unconjugated
anti-Aggrecan (ACAN) (AA 101-220) antibodyACAN Reaktivität: Human, Ratte, Maus, Kaninchen WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Aggrecan (ACAN) antibodyACAN Reaktivität: Human WB, IF (p), FACS Wirt: Kaninchen Monoclonal 24GB3415 unconjugated Recombinant Antibody
anti-Aggrecan (ACAN) (AA 601-700) antibodyACAN Reaktivität: Ratte, Maus, Kaninchen ICC, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Aggrecan (ACAN) (N-Term) antibodyACAN Reaktivität: Human, Ratte, Maus WB, IHC, ICC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Aggrecan (ACAN) (C-Term) antibodyACAN Reaktivität: Human, Ratte, Hamster, Affe IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Aggrecan (ACAN) (AA 587-684) antibodyACAN Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Aggrecan (ACAN) (AA 2066-2316) antibodyACAN Reaktivität: Rind (Kuh) WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- Aggrecan (ACAN)
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Andere Bezeichnung
- Aggrecan
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Hintergrund
- Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS.Synonyms: ACAN, AGC1, CSPG1, Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan core protein 1, MSK16
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Gen-ID
- 9606
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UniProt
- P16112
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Pathways
- Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
Target
-
