LI Cadherin Antikörper (AA 24-132)

Produktnummer ABIN782351

Der Maus Monoklonal anti-LI Cadherin Antikörper wird verwendet zum Nachweis von LI Cadherin in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für LI Cadherin Antikörper (AA 24-132) (ABIN782351)

Target: LI Cadherin

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LI Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 3H2

Produktdetails anti-LI Cadherin Antikörper

Bindungsspezifität: AA 24-132

Spezifität: Recognizes Cadherin-17

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein A Chromatography

Immunogen: CDH17 antibody was raised against CDH17 (NP_004054, 24 a.a. ~ 132 a.a) partial recombinant protein with GST tag.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.2

Handhabung: Avoid freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C or -80 °C.

Details zu LI Cadherin

Target: LI Cadherin

Andere Bezeichnung: Cadherin-17

Hintergrund: The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin beta, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.Synonyms: CDH17, HPT-1, HPT1, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin

Gen-ID: 1015

NCBI Accession: NP_001138135

UniProt: Q12864