SAA Antikörper

Produktnummer ABIN782005

Dieser Maus Monoklonal Antikörper detektiert spezifisch SAA in WB, EIA, ELISA (Detection) und ELISA (Capture). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SAA Antikörper (ABIN782005)

Target: SAA (Serum Amyloid A (SAA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SAA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), ELISA (Detection), ELISA (Capture)

Klon: B336A

Produktdetails anti-SAA Antikörper

Spezifität: This antibody recognizes native and recombinant Serum Amyloid A (SAA).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Human recombinant SAA, conjugated with carrier protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 2.9 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu SAA

Target: SAA (Serum Amyloid A (SAA))

Andere Bezeichnung: Serum Amyloid A Protein (SAA)

Hintergrund: The Serum Amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP. SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a "houekeeping" role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid artheritis.Synonyms: SAA1, SAA2

Gen-ID: 6288

NCBI Accession: NP_000322

UniProt: P02735