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CD163 Antikörper

CD163 Reaktivität: Human WB, FACS, IP, IHC (fro) Wirt: Maus Monoclonal GHI-61 unconjugated
Produktnummer ABIN781802
  • Target Alle CD163 Antikörper anzeigen
    CD163
    Reaktivität
    • 142
    • 48
    • 31
    • 29
    • 19
    • 5
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 111
    • 59
    • 1
    Maus
    Klonalität
    • 97
    • 73
    • 1
    Monoklonal
    Konjugat
    • 58
    • 19
    • 15
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD163 Antikörper ist unkonjugiert
    Applikation
    • 111
    • 83
    • 53
    • 41
    • 27
    • 27
    • 27
    • 26
    • 22
    • 20
    • 15
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This antibody recognizes CD163, an approximately 130 kDa high affinity scavenger receptor expressed mainly on monocytes and macrophages, which binds hemoglobin-haptoglobin complex.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Protein-A affinity chromatography
    Reinheit
    > 95 % pure (by SDS-PAGE)
    Immunogen
    Hairy cell leukemia cells
    Klon
    GHI-61
    Isotyp
    IgG1
    Top Product
    Discover our top product CD163 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    CD163
    Andere Bezeichnung
    CD163 (CD163 Produkte)
    Hintergrund
    CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.Synonyms: Hemoglobin scavenger receptor, M130, Macrophage marker, Scavenger receptor cysteine-rich type 1 protein M130
    Gen-ID
    9332
    NCBI Accession
    NP_004235
    UniProt
    Q86VB7
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