CD16 Antikörper
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- Target Alle CD16 Antikörper anzeigen
- CD16
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD16 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- The antibody recognizes CD16, the low affinity receptor for IgG (FcγRIII). It detects both isoforms.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Affinity chromatography
- Klon
- C127
- Isotyp
- IgG1
- Top Product
- Discover our top product CD16 Primärantikörper
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anti-CD16 (CD16) antibody
CD16 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro) Wirt: Maus Monoclonal 3G8 unconjugated
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human, Non-Human Primate FACS, IP Wirt: Maus Monoclonal LNK16 unconjugated
anti-CD16 (CD16) antibody (FITC)CD16 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal LNK16 FITC
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human FACS, IP, WB Wirt: Maus Monoclonal MEM-154 unconjugated
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human, Schwein, Non-Human Primate FACS Wirt: Maus Monoclonal MEM-168 unconjugated
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human FACS, IP, Func, WB Wirt: Maus Monoclonal MEM-154 unconjugated
anti-CD16 (CD16) antibody (Biotin)CD16 Reaktivität: Human FACS, IP, WB Wirt: Maus Monoclonal MEM-154 Biotin
anti-CD16 (CD16) (AA 17-208) antibodyCD16 Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 2G10A9 unconjugated
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human, Non-Human Primate FACS, IP, Func, IHC (fro) Wirt: Maus Monoclonal 3G8 unconjugated
anti-CD16 (CD16) antibodyCD16 Reaktivität: Human FACS Wirt: Maus Monoclonal GRM1 unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Reconstitute by adding 0.5 mL distilled water.
- Buffer
- Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 5 mg/mL bovine serum albumin (BSA), and 0.09 % sodium azide as a preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Lyophilized product can be stored at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
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- Target
- CD16
- Andere Bezeichnung
- CD16 (CD16 Produkte)
- Hintergrund
- CD16 is expressed on the majority of NK cells, on granulocytes, monocytes and macrophages, and on a subset of T cells. CD16 is involved in antibody-dependent cellular cytotoxicity (ADCC). This molecule is encoded by FcγRIII-A or FcγRIII-B genes. The genetic heterogeneity of FcγRIII generates alternative membrane-anchored proteins with distinct signalling capacities when cross-linked by immune complexes. CD16 exists in two distinct forms, as a single-pass type I integral membrane protein (CD16a), and as a glycosyl phosphatidyl inositol (GPI) form (CD16b). In humans, the transmembrane form is expressed on NK cells and macrophages while the GPI linked form is expressed on granulocytes.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A
- Gen-ID
- 2214
- NCBI Accession
- NP_000560
- UniProt
- P08637
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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