Ferritin Antikörper

Produktnummer ABIN781724

Produktdetails anti-Ferritin Antikörper

Target: Ferritin (FE)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ferritin Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Affinity chromatography

Immunogen: Ferritin from human spleen and liver

Klon: MAb 44

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Reconstitute by adding 0.5 mL distilled water.

Buffer: Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 10 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.01 % thimerosal as a preservative

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Details zu Ferritin

Target: Ferritin (FE)

Andere Bezeichnung: Ferritin (FE Produkte)

Synonyme: 1HCH antikoerper, BEST:LD36673 antikoerper, CG2216 antikoerper, Dmel\\CG2216 antikoerper, FER1 antikoerper, FER1HCH antikoerper, Fer-L antikoerper, Fer1 antikoerper, Fer1HC antikoerper, FerHCH antikoerper, HCH antikoerper, T21 antikoerper, T9 antikoerper, fer1 antikoerper, fer1hch antikoerper, l(3)00451 antikoerper, l(3)j10B4 antikoerper, SFerH-1 antikoerper, SOF-35 antikoerper, SOF-5L antikoerper, NV13011 antikoerper, ACP1 antikoerper, F8A5.24 antikoerper, F8A5_24 antikoerper, Ferritin 1 heavy chain homologue antikoerper, ferritin light chain antikoerper, ferritin antikoerper, chromosome 26 open reading frame, human C10orf131 antikoerper, hyaluronan and proteoglycan link protein 2 antikoerper, NAD(P)-linked oxidoreductase superfamily protein antikoerper, Fer1HCH antikoerper, H-1 antikoerper, YPDSF_1340 antikoerper, ftnA antikoerper, Ft antikoerper, C26H10orf131 antikoerper, HAPLN2 antikoerper, AT1G60730 antikoerper

Hintergrund: Ferritin consists of a mineral core of hydrated ferric oxide, and a multi-subunit protein shell which englobes the former and assures its solubility in an aqueous environment. It is mainly localized intracellularly in cells of the reticuloendothelial system as well as in liver, spleen and bone marrow. Elevated serum levels are found in patients with iron overload and in other diseases such as pernicious anaemia, chronic inflammations such as rheumatoid arthritis (RA), hepatocellular carcinoma and Hodgkin's disease. Ferritin consists of two components, the apoferritin and the iron core (FeIII - hydroxyphosphate-micelle). The apoferritin is a globular protein built up of 24 subunits that can bind up to 4500 iron atoms. Other non-ferrous metal ions such as Al or Be can also bind to ferritin, which acts partly as a metal ion detoxicant.Synonyms: FTH, FTL, Ferritin H subunit, Ferritin L subunit

Pathways: Transition Metal Ion Homeostasis