This Monoclonal HH1 antibody recognizes the CD37 antigen. Antigen Distribution Isolated cells: The antibody strongly stains approximately 2-10 % of human peripheral blood mononuclear cells in flow cytometry. CD37 is present at low density on resting and activated T cells, neutrophils, monocytes and some myelomonocytic leukemia cells. Tissue Sections: The antibody shows a B cell restricted staining pattern.
TSPAN26
Reaktivität: Human
FACS, ELISA
Wirt: Kaninchen
Monoclonal
DM166
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS, pH 7.2, 0.09 % Sodium Azide, 5 mg/mL BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
Target
CD37 (TSPAN26)
(Tetraspanin 26 (TSPAN26))
Andere Bezeichnung
CD37
Hintergrund
CD37 is strongly expressed on normal and neoplastic mature B lymphocytes. In B-cell ontogeny, the antigen appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. Due to its strong expression, CD37 is a valuable and stable marker for peripheral mature B cells and malignancies thereof. CD37 is extensively glycosylated and typically precipitates as a broad band ranging from 42 to 52kD.Synonyms: Leukocyte antigen CD37, TSPAN26, Tetraspanin-26