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CD19 Antikörper (APC)

CD19 Reaktivität: Human FACS Wirt: Maus Monoclonal 4G7 APC
Produktnummer ABIN781694
  • Target Alle CD19 Antikörper anzeigen
    CD19 (CD19 Molecule (CD19))
    Reaktivität
    • 304
    • 180
    • 48
    • 30
    • 19
    • 10
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 185
    • 140
    • 63
    • 4
    Maus
    Klonalität
    • 260
    • 128
    • 2
    Monoklonal
    Konjugat
    • 117
    • 25
    • 22
    • 21
    • 18
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD19 Antikörper ist konjugiert mit APC
    Applikation
    • 274
    • 120
    • 75
    • 66
    • 61
    • 42
    • 23
    • 21
    • 17
    • 14
    • 14
    • 10
    • 10
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody recognizes CD19 (B4), a 95 kDa type I transmembrane glycoprotein of immunoglobulin superfamily, expressed on B lymphocytes and follicular dendritic cells, it is lost on plasma cells.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Immunogen
    Human CCL (chronic lymphocytic leukemia) cells
    Klon
    4G7
    Isotyp
    IgG1
    Top Product
    Discover our top product CD19 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Lagerung
    4 °C
  • Target
    CD19 (CD19 Molecule (CD19))
    Andere Bezeichnung
    CD19 (CD19 Produkte)
    Synonyme
    B4 antikoerper, CVID3 antikoerper, AW495831 antikoerper, CD19 antikoerper, CD19 molecule antikoerper, CD19 antigen antikoerper, CD19 antikoerper, Cd19 antikoerper
    Hintergrund
    CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12
    Gen-ID
    930
    NCBI Accession
    NP_001761
    UniProt
    P15391
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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