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CD28 Antikörper

CD28 Reaktivität: Human, Primate FACS, WB, IF, IP, Func, IHC (fro) Wirt: Maus Monoclonal CD28-2 unconjugated
Produktnummer ABIN781619
  • Target Alle CD28 Antikörper anzeigen
    CD28
    Reaktivität
    • 180
    • 129
    • 60
    • 38
    • 21
    • 20
    • 12
    • 12
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Primate
    Wirt
    • 142
    • 78
    • 28
    • 18
    • 8
    • 3
    • 2
    Maus
    Klonalität
    • 199
    • 74
    • 3
    Monoklonal
    Konjugat
    • 92
    • 30
    • 28
    • 20
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD28 Antikörper ist unkonjugiert
    Applikation
    • 203
    • 93
    • 49
    • 48
    • 39
    • 30
    • 29
    • 26
    • 20
    • 17
    • 13
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This antibody reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Non-Human Primates
    Aufreinigung
    Protein A affinity chromatography
    Reinheit
    > 95 % (by SDS-PAGE)
    Klon
    CD28-2
    Isotyp
    IgG1
    Top Product
    Discover our top product CD28 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    CD28
    Andere Bezeichnung
    CD28 (CD28 Produkte)
    Synonyme
    Tp44 antikoerper, CD28RNA antikoerper, cd28 antikoerper, CD28 molecule antikoerper, CD28 antigen antikoerper, Cd28 molecule antikoerper, CD28 molecule L homeolog antikoerper, CD28 antikoerper, Cd28 antikoerper, cd28.L antikoerper
    Hintergrund
    CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Synonyms: T-cell-specific surface glycoprotein CD28, TP44
    Gen-ID
    940
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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