HSP70 1A Antikörper
Kurzübersicht für HSP70 1A Antikörper (ABIN781228)
Target
Alle HSP70 1A (HSPA1A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Cytoplasm
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Aufreinigung
- Protein G-Sepharose affinity purified.
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Immunogen
- Recombinant fragment of human HSPA1A (C-terminus).
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide and 50% glycerol, 1%BSA, PBS, pH7.4.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))
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Andere Bezeichnung
- HSPA1A
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Hintergrund
- Hsp70 genes encode abundant heat-inducible 70-kDa hsps (hsp70s). In most eukaryotes hsp70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 5O% identity. The structure of this ATP binding domain displays multiple features of nucleotide binding proteins. The molecular chaperones of the hsp70 family recognize and bind to nascent polypeptide chains as well as partially folded intermediates of proteins preventing their aggregation and misfolding.
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Molekulargewicht
- 70kDa
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NCBI Accession
- NM_005345
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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