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Lambda-IgLC Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Lambda-IgLC in FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.
Produktnummer ABIN775708

Kurzübersicht für Lambda-IgLC Antikörper (ABIN775708)

Target

Lambda-IgLC (lambda Light Chain (Lambda-IgLC))

Reaktivität

  • 27
  • 15
Human

Wirt

  • 22
  • 19
  • 1
Maus

Klonalität

  • 22
  • 20
Monoklonal

Konjugat

  • 10
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Lambda-IgLC Antikörper ist unkonjugiert

Applikation

  • 20
  • 15
  • 13
  • 13
  • 9
  • 8
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

1-155-2
  • Verwendungszweck

    Anti-Hu Ig Lambda Light Chain Purified

    Spezifität

    The mouse monoclonal antibody 1-155-2 recognizes lambda light chains (22.5 kDa) of human immunoglobulin.

    Kreuzreaktivität (Details)

    Human

    Aufreinigung

    Purified by protein-A affinity chromatography.

    Reinheit

    > 95 % (by SDS-PAGE)

    Immunogen

    Human IgA1 lambda myeloma protein

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    Flow cytometry: Recommended dilution: 1-4 μg/mL. Extracellular and intracellular staining.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Do not freeze.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Do not freeze.
  • Tierens, Holte, Warsame, Ikonomou, Wang, Chan, Delabie: "Low levels of monoclonal small B cells in the bone marrow of patients with diffuse large B-cell lymphoma of activated B-cell type but not of germinal center B-cell type." in: Haematologica, Vol. 95, Issue 8, pp. 1334-41, (2010) (PubMed).

    Bahler, Pindzola, Swerdlow: "Splenic marginal zone lymphomas appear to originate from different B cell types." in: The American journal of pathology, Vol. 161, Issue 1, pp. 81-8, (2002) (PubMed).

    Kubagawa, Gathings, Levitt, Kearney, Cooper: "Immunoglobulin isotype expression of normal pre-B cells as determined by immunofluorescence." in: Journal of clinical immunology, Vol. 2, Issue 4, pp. 264-9, (1983) (PubMed).

  • Target

    Lambda-IgLC (lambda Light Chain (Lambda-IgLC))

    Andere Bezeichnung

    Ig Lambda Light Chain

    Hintergrund

    Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.,Immunoglobulin lambda, Igl

    Molekulargewicht

    22.5 kDa
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