CD90 Antikörper

Produktnummer ABIN775703

Produktdetails anti-CD90 Antikörper

Target: CD90 (THY1)

Reaktivität: Human, Schwein, Pferd, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD90 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Spezifität: The mouse monoclonal antibody 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.

Keine Kreuzreaktivität: Hund

Kreuzreaktivität (Details): Human, Non-Human Primates, Porcine, Equine (Horse)

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: HEL erythroleukemia cells

Klon: 5E10

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-3 μg/mL.
Immunohistochemistry: Recommended dilution: 5-10 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Konservierungsmittel: Azide free

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-CD90 Antikörper (ABIN775703)

Hoppstädter, Diesel, Zarbock, Breinig, Monz, Koch, Meyerhans, Gortner, Lehr, Huwer, Kiemer: "Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages." in: Respiratory research, Vol. 11, pp. 124, (2010) (PubMed).

Kroeze, Jurgens, Doulabi, van Milligen, Scheper, Gibbs: "Chemokine-mediated migration of skin-derived stem cells: predominant role for CCL5/RANTES." in: The Journal of investigative dermatology, Vol. 129, Issue 6, pp. 1569-81, (2009) (PubMed).

Carlsten, Björkström, Norell, Bryceson, van Hall, Baumann, Hanson, Schedvins, Kiessling, Ljunggren, Malmberg: "DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells." in: Cancer research, Vol. 67, Issue 3, pp. 1317-25, (2007) (PubMed).

Seiffert, Brossart, Cant, Cella, Colonna, Brugger, Kanz, Ullrich, Bühring: "Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells." in: Blood, Vol. 97, Issue 9, pp. 2741-9, (2001) (PubMed).

Ito, Inaba, Inaba, Toki, Sogo, Iguchi, Adachi, Yamaguchi, Amakawa, Valladeau, Saeland, Fukuhara, Ikehara: "A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 3, pp. 1409-19, (1999) (PubMed).

Details zu CD90

Target: CD90 (THY1)

Andere Bezeichnung: CD90 (THY1 Produkte)

Synonyme: CD90 antikoerper, CD7 antikoerper, T25 antikoerper, Thy-1 antikoerper, Thy-1.2 antikoerper, Thy1.1 antikoerper, Thy1.2 antikoerper, Thy-1 cell surface antigen antikoerper, thymus cell antigen 1, theta antikoerper, THY1 antikoerper, Thy1 antikoerper

Hintergrund: Thy-1 cell surface antigen,CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.,Thy-1

Gen-ID: 7070

UniProt: P04216

Pathways: Cell-Cell Junction Organization