RASA2 Antikörper (AA 765-849) (Biotin)

Produktnummer ABIN763468

Produktdetails anti-RASA2 Antikörper (Biotin)

Target: RASA2 (RAS P21 Protein Activator 2 (RASA2))

Bindungsspezifität: AA 765-849

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASA2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RASGAP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu RASA2

Target: RASA2 (RAS P21 Protein Activator 2 (RASA2))

Andere Bezeichnung: RASA2 (RASA2 Produkte)

Synonyme: GAP1M antikoerper, 5430433H21Rik antikoerper, AA517451 antikoerper, AU023900 antikoerper, GAP1m antikoerper, RAS p21 protein activator 2 antikoerper, RASA2 antikoerper, Rasa2 antikoerper

Hintergrund:

Synonyms: GAP1M, GTPase activating protein of RAS, Ras GTPase activating protein 2, Ras GTPase-activating protein 2, RAS p21 protein activator 2, RASA2, RASA2_HUMAN, RASGAP.

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein, a compound suggested to function as a second messenger. [provided by RefSeq, Jul 2008].

Gen-ID: 8826