ST5 Antikörper (AA 1051-1137)

Produktnummer ABIN762611

Der Kaninchen Polyklonal Anti-ST5-Antikörper wurde für ELISA, IF (cc), IF (p), IHC (fro) und IHC (p) validiert. Er ist geeignet, ST5 in Proben von Human zu detektieren.

Kurzübersicht für ST5 Antikörper (AA 1051-1137) (ABIN762611)

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ST5 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ST5 Antikörper

Bindungsspezifität: AA 1051-1137

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ST5/DENND2B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Andere Bezeichnung: St5

Hintergrund:

Synonyms: DENND2B, DENN domain containing protein 2B, HeLa tumor suppression 1, DENN domain-containing protein 2B, DENN/MADD domain containing 2B, DENND2B, HTS1, p126, ST 5, ST5, ST5_HUMAN, Suppression of tumorigenicity 5, Suppression of tumorigenicity 5 protein.

Background: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008].

Gen-ID: 6764