RIN1 Antikörper (AA 201-300) (Cy3)
Kurzübersicht für RIN1 Antikörper (AA 201-300) (Cy3) (ABIN762344)
Target
Alle RIN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 201-300
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Kreuzreaktivität
 - Ratte
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Homologie
 - Human,Mouse,Cow,Pig
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Aufreinigung
 - Purified by Protein A.
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Immunogen
 - KLH conjugated synthetic peptide derived from human RIN1
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Isotyp
 - IgG
 
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Applikationshinweise
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                        IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1 μg/μL
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Buffer
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
 - ProClin
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Vorsichtsmaßnahmen
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
 - 12 months
 
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- RIN1 (Ras and Rab Interactor 1 (RIN1))
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Andere Bezeichnung
 - RIN1
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Hintergrund
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Synonyms: Ras and Rab interactor 1, ras inhibitor 1, ras inhibitor, RIN1_HUMAN, Ras inhibitor JC99, ras inhibitor RIN1, Ras interaction/interference protein 1, RIN 1.
Background: RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.
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Gen-ID
 - 9610
 
Target
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