LLGL1 + LLGL2 (pSer650), (pSer654) Antikörper (Biotin)

Produktnummer ABIN761983

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in WB, ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für LLGL1 + LLGL2 (pSer650), (pSer654) Antikörper (Biotin) (ABIN761983)

Target: LLGL1 + LLGL2

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Bindungsspezifität: pSer650, pSer654

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Antigendetails

Target: LLGL1 + LLGL2

Andere Bezeichnung: LLGL1 + LLGL2+

Hintergrund:

Synonyms: LLGL1 + LLGL2 phospho S650 + S654, LLGL1 + LLGL2 phospho Ser650 + Ser654, p-LLGL1 + p-LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650 + Ser654, p-LLGL1/LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650/654, DLG4, HGL, HUGL, HUGL1, lethal giant larvae homolog 1, lethal giant larvae homolog 2, Lethal2 giant larvae protein homolog 1, Lethal2 giant larvae protein homolog 2, LGL2, LLGL, L2GL1_HUMAN, L2GL2_HUMAN.

Background: LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

Gen-ID: 3996