ZBTB33 Antikörper (AA 100-180)
Kurzübersicht für ZBTB33 Antikörper (AA 100-180) (ABIN8125797)
Target
Alle ZBTB33 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 100-180
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Verwendungszweck
- KAISO Antibody
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Spezifität
- KAISO Polyclonal Antibody detects endogenous levels of protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from human protein . at AA range: 100-180
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000 ELISA 1:5000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))
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Andere Bezeichnung
- KAISO
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Hintergrund
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Background: This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear impor
Gene Name: ZBTB33 KAISO ZNF348
Protein Name: Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33)
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Gen-ID
- 10009
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UniProt
- Q86T24
Target
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