PROC Antikörper (Cleaved-Leu179, Light Chain)

Produktnummer ABIN8125721

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PROC in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PROC Antikörper (Cleaved-Leu179, Light Chain) (ABIN8125721)

Target: PROC (Vitamin K-dependent protein C (PROC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PROC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-PROC Antikörper

Bindungsspezifität: Cleaved-Leu179, Light Chain

Verwendungszweck: PROC (light chain, Cleaved-Leu179) Antibody

Spezifität: This antibody detects endogenous levels of Human PROC (light chain, Cleaved-Leu179, protein was cleaved amino acid sequence between 179-180 )

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PROC

Target: PROC (Vitamin K-dependent protein C (PROC))

Andere Bezeichnung: PROC

Hintergrund:

Synonyms: Vitamin K-dependent protein C (EC 3.4.21.69, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain, Vitamin K-dependent protein C heavy chain, Activation peptide]

Background: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],

Gene Name: PROC

Protein Name: PROC (light chain, Cleaved-Leu179)

Gen-ID: 5624

UniProt: P04070