TNK1 Antikörper (pTyr277)

Produktnummer ABIN8125506

Der Kaninchen Polyklonal anti-TNK1 Antikörper wird verwendet zum Nachweis von TNK1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für TNK1 Antikörper (pTyr277) (ABIN8125506)

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TNK1 Antikörper

Bindungsspezifität: pTyr277

Verwendungszweck: TNK1 (Phospho Tyr277) Antibody

Spezifität: This antibody detects endogenous levels of Human TNK1 (phospho-Tyr277)

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human TNK1 (Tyr277)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu TNK1

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Andere Bezeichnung: TNK1

Hintergrund:

Synonyms: Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)

Background: The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Gene Name: TNK1

Protein Name: TNK1 (Tyr277)

Gen-ID: 8711

UniProt: Q13470