TTF1 Antikörper

Produktnummer ABIN8125285

Der Kaninchen Monoklonal anti-TTF1 Antikörper (Klon AB2124) (ABIN8125285) detektiert spezifisch TTF1 in WB, IHC, ELISA, IF und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für TTF1 Antikörper (ABIN8125285)

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TTF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: AB2124

Produktdetails anti-TTF1 Antikörper

Verwendungszweck: TTF1 Rabbit mAb

Spezifität: This antibody detects endogenous levels of TTF1 protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu TTF1

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Andere Bezeichnung: TTF1

Hintergrund:

Synonyms: AV026640, BCH, Benign chorea, BHC, Homeobox protein NK 2 homolog A, Homeobox protein NK-2 homolog A, Homeobox protein Nkx 2. 1, Homeobox protein Nkx-2. 1, Homeobox protein Nkx2. 1, NK 2, NK 2 homolog A, NK2, NK2 homeobox 1, NK2, drosophila, homolog of, A, NK2. 1, Mouse, homolog of, Nkx 2 1, NKX 2. 1, NKX 2A, NKX2 1, Nkx2-1, NKX2. 1, NKX21_HUMAN, NKX2A, T EBP, T/EBP, TEBP, Thyroid nuclear factor 1, Thyroid nuclear factor, Thyroid specific enhancer binding protein, Thyroid transcription factor 1, Tin man, Tinman, TITF 1, TITF1, TTF 1, TTF-1, TTF1

Background: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias &apos, TTF1&apos, with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],

Gene Name: NKX2-1

Protein Name: TTF1

Gen-ID: 7080

UniProt: P43699

Pathways: Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour