TFE3 Antikörper (AA 100-200)

Produktnummer ABIN8125277

Dieser Maus Monoklonal Antikörper detektiert spezifisch TFE3 in WB, ELISA, IHC, IF und IP. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Rind (Kuh).

Kurzübersicht für TFE3 Antikörper (AA 100-200) (ABIN8125277)

Target: TFE3 (Transcription Factor E3 (TFE3))

Reaktivität: Human, Maus, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TFE3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: AB2352

Produktdetails anti-TFE3 Antikörper

Bindungsspezifität: AA 100-200

Verwendungszweck: TFE3 mouse mAb

Spezifität: This antibody detects endogenous levels of TFE3 protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 100 - 200 of the human TFE3 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | IP, 0. 5 μg-1:4 μg antibody for 200 μg-1:400 μg extracts of whole cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu TFE3

Target: TFE3 (Transcription Factor E3 (TFE3))

Andere Bezeichnung: TFE3

Hintergrund:

Synonyms: Transcription factor E3, Class E basic helix-loop-helix protein 33 (bHLHe33) , BHLHE33, TFE3

Background: transcription factor binding to IGHM enhancer 3 (TFE3) Homo sapiens This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma) , NONO (non-POU domain containing, octamer-binding) , and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1) , among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],

Gene Name: TFE3

Protein Name: TFE3

Gen-ID: 7030

UniProt: P19532