TBXAS1 Antikörper

Produktnummer ABIN8125194

Der Kaninchen Polyklonal anti-TBXAS1 Antikörper wird verwendet zum Nachweis von TBXAS1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für TBXAS1 Antikörper (ABIN8125194)

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBXAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TBXAS1 Antikörper

Verwendungszweck: TXA synthase Antibody

Spezifität: TXA synthase Polyclonal Antibody detects endogenous levels of TXA synthase protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human TXA synthase.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu TBXAS1

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Andere Bezeichnung: TXA synthase

Hintergrund:

Synonyms: TBXAS1, CYP5, CYP5A1, Thromboxane-A synthase, TXA synthase, TXS, Cytochrome P450 5A1

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

Gene Name: TBXAS1

Protein Name: Thromboxane-A synthase

Gen-ID: 6916

UniProt: P24557