Synovial Sarcoma, X Breakpoint 2B (SSX2B) (AA 139-188) Antikörper

Produktnummer ABIN8125065

Der Kaninchen Polyklonal anti-Synovial Sarcoma, X Breakpoint 2B Antikörper wird verwendet zum Nachweis von Synovial Sarcoma, X Breakpoint 2B in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF und IHC.

Kurzübersicht für Synovial Sarcoma, X Breakpoint 2B (SSX2B) (AA 139-188) Antikörper (ABIN8125065)

Target: Synovial Sarcoma, X Breakpoint 2B (SSX2B)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: AA 139-188

Verwendungszweck: SSX Antibody

Spezifität: SSX Polyclonal Antibody detects endogenous levels of SSX protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human SSX1/2/3/4/5/6/7/8/9. AA range:139-188

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Antigendetails

Target: Synovial Sarcoma, X Breakpoint 2B (SSX2B)

Andere Bezeichnung: SSX

Hintergrund:

Synonyms: SSX1, Protein SSX1, Cancer/testis antigen 5.1, CT5.1, Synovial sarcoma, X breakpoint 1, SSX2, SSX2A, SSX2B, Protein SSX2, Cancer/testis antigen 5.2, CT5.2, Synovial sarcoma, X breakpoint 2, Tumor antigen HOM-MEL-40, SSX3, Protein SSX3, Cancer/testis antigen 5.3, CT5.3, SSX4, SSX4A, SSX4B, Protein SSX4, Cancer/testis antigen 5.4, CT5.4, SSX5, Protein SSX5, SSX6, Putative protein SSX6, SSX7, Protein SSX7, SSX8, Protein SSX8, SSX9, Protein SSX9

Background: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X,18)(p11.2,q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2013],

Gene Name: SSX1/SSX2/SSX3/SSX4/SSX5/SSX6/SSX7/SSX8/SSX9

Protein Name: Protein SSX1/Protein SSX2/Protein SSX3/Protein SSX4/Protein SSX5/Protein SSX6/Protein SSX7/Protein SSX8/Protein SSX9

Gen-ID: 6756

UniProt: Q16384