STARD4 Antikörper

Produktnummer ABIN8124947

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch STARD4 in WB, ICC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für STARD4 Antikörper (ABIN8124947)

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser STARD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: AB2258

Produktdetails anti-STARD4 Antikörper

Verwendungszweck: STARD4 Rabbit mAb

Spezifität: This antibody detects endogenous levels of STARD4 protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:1000-1:5000 | IF, 1:100-1:300 |

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu STARD4

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Andere Bezeichnung: STARD4

Hintergrund:

Synonyms: STARD4, StAR-related lipid transfer protein 4 , START domain-containing protein 4, StARD4,

Background: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e. g. , SREBP1, MIM 184756) and by liver X receptors (e. g. , LXRA, MIM 602423) . Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617) . STAR is homologous to a family of proteins containing a 200-to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al. , 2002 [PubMed 12011452]) . [supplied by OMIM, Mar 2008]

Gene Name: STARD4

Protein Name: STARD4

Gen-ID: 134429

UniProt: Q96DR4