SNX13 Antikörper (AA 602-652)

Produktnummer ABIN8124858

Der Kaninchen Polyklonal anti-SNX13 Antikörper wird verwendet zum Nachweis von SNX13 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für SNX13 Antikörper (AA 602-652) (ABIN8124858)

Target: SNX13 (Sorting Nexin 13 (SNX13))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SNX13 Antikörper

Bindungsspezifität: AA 602-652

Verwendungszweck: SNX13 Antibody

Spezifität: This antibody detects endogenous levels of SNX13 at Human/Mouse

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human SNX13 AA range: 602-652

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu SNX13

Target: SNX13 (Sorting Nexin 13 (SNX13))

Andere Bezeichnung: SNX13

Hintergrund:

Synonyms: Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)

Background: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008],

Gene Name: SNX13 KIAA0713

Protein Name: SNX13

Gen-ID: 23161

UniProt: Q9Y5W8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling