Smad1/9 Antikörper (AA 400-465)
Kurzübersicht für Smad1/9 Antikörper (AA 400-465) (ABIN8124750)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 400-465
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Verwendungszweck
- Smad1/9 mouse mAb
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Spezifität
- This antibody detects endogenous levels of Smad1/9 protein.
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Aufreinigung
- The antibody was purified by protein G affinity chromatography.
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Immunogen
- A synthetic peptide corresponding to the amino acid region 400 - 465 of the human Smad1/9 protein.
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Isotyp
- IgG
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anti-Smad1/9 (C-Term) antibody
Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Smad1/9 (pSer465), (pSer467) antibodyReaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at-20°C. Avoid freeze / thaw cycles.
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- Smad1/9
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Hintergrund
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Synonyms: Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1 (SMAD 1, Smad1, hSMAD1) , Transforming growth factor-beta-signaling protein 1 (BSP-1) , SMAD1, BSP1, MADH1, MADR1, Mothers against decapentaplegic homolog 9, MAD homolog 9, Mothers against DPP homolog 9, Madh6, SMAD family member 9 (SMAD 9, Smad9) , SMAD9, MADH6, MADH9, SMAD8
Background: SMAD family member 1 (SMAD1) Homo sapiens The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs) , which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med
Gene Name: SMAD1 SMAD9
Protein Name: Smad1/9
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Gen-ID
- 4086
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UniProt
- Q15797
Target
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