SMAD5 Antikörper (pSer463, Ser465)

Produktnummer ABIN8124746

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch SMAD5 in WB, IHC, ELISA, IF und IP. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für SMAD5 Antikörper (pSer463, Ser465) (ABIN8124746)

Target: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser SMAD5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: AB1609

Produktdetails anti-SMAD5 Antikörper

Bindungsspezifität: pSer463, Ser465

Verwendungszweck: SMAD5 (Phospho Ser463/Ser465) Rabbit mAb

Spezifität: The antibody detects endogenous levels of SMAD5 protein only when phosphorylated at Ser463 and Ser465. The antibody does not cross-react with SMAD5 phosphorylated at other sites.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu SMAD5

Target: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Andere Bezeichnung: SMAD5

Hintergrund:

Synonyms: SMAD5, MADH5, Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, JV5-1, SMAD family member 5, SMAD 5, Smad5, hSmad5

Background: The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],

Gene Name: SMAD5

Protein Name: SMAD5 (Phospho Ser463/Ser465)

Gen-ID: 4090

UniProt: Q99717