SIGLEC-5,SIGLEC-14 (AA 91-140) Antikörper

Produktnummer ABIN8124677

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SIGLEC-5,SIGLEC-14 in ELISA, IF, WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SIGLEC-5,SIGLEC-14 (AA 91-140) Antikörper (ABIN8124677)

Target: SIGLEC-5,SIGLEC-14

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: AA 91-140

Verwendungszweck: Siglec-5/14 Antibody

Spezifität: Siglec-5/14 Polyclonal Antibody detects endogenous levels of Siglec-5/14 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14 at AA range: 91-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Antigendetails

Target: SIGLEC-5,SIGLEC-14

Andere Bezeichnung: Siglec-5/14

Hintergrund:

Synonyms: SIGLEC5, CD33L2, OBBP2, Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, OB-binding protein 2, CD170, SIGLEC14, Sialic acid-binding Ig-like lectin 14, Siglec-14

Background: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012],

Gene Name: SIGLEC5/SIGLEC14

Protein Name: Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14

Gen-ID: 8778

UniProt: O15389