Septin 5 Antikörper (AA 180-260)

Produktnummer ABIN8124586

Der Kaninchen Polyklonal anti-Septin 5 Antikörper (ABIN8124586) detektiert spezifisch Septin 5 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für Septin 5 Antikörper (AA 180-260) (ABIN8124586)

Target: Septin 5 (SEPT5)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Septin 5 Antikörper

Bindungsspezifität: AA 180-260

Verwendungszweck: Septin 5 Antibody

Spezifität: Septin 5 Polyclonal Antibody detects endogenous levels of Septin 5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Septin 5 . at AA range: 180-260

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Septin 5

Target: Septin 5 (SEPT5)

Andere Bezeichnung: Septin 5

Hintergrund:

Synonyms: SEPT5, PNUTL1, Septin-5, Cell division control-related protein 1, CDCrel-1, Peanut-like protein 1

Background: septin 5(SEPT5) Homo sapiens This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010],

Gene Name: SEPT5

Protein Name: Septin-5

Gen-ID: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis