Sclerostin Antikörper (AA 130-210)
Kurzübersicht für Sclerostin Antikörper (AA 130-210) (ABIN8124552)
Target
Alle Sclerostin (SOST) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 130-210
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Verwendungszweck
- Sclerostin Antibody
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Spezifität
- Sclerostin Polyclonal Antibody detects endogenous levels of Sclerostin protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from Sclerostin . at AA range: 130-210
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- Sclerostin (SOST)
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Andere Bezeichnung
- Sclerostin
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Hintergrund
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Synonyms: SOST, Sclerostin
Background: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008],
Gene Name: SOST
Protein Name: Sclerostin
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Gen-ID
- 50964
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UniProt
- Q9BQB4
Target
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