REG4 Antikörper

Produktnummer ABIN8124301

Der Kaninchen Polyklonal anti-REG4 Antikörper (ABIN8124301) detektiert spezifisch REG4 in IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für REG4 Antikörper (ABIN8124301)

Target: REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REG4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-REG4 Antikörper

Verwendungszweck: Reg IV Antibody

Spezifität: Reg IV Polyclonal Antibody detects endogenous levels of Reg IV protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Reg IV.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu REG4

Target: REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))

Andere Bezeichnung: Reg IV

Hintergrund:

Synonyms: REG4, GISP, RELP, Regenerating islet-derived protein 4, REG-4, Gastrointestinal secretory protein, REG-like protein, Regenerating islet-derived protein IV, Reg IV

Background: function:May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.,induction:Up-regulated by mucosal injury from active Crohn's disease or ulcerative colitis. Up-regulated in colorectal tumors. Up-regulated in epithelial cells at regenerating margins of peptic ulcers in the stomach and duodenum.,online information:Regenerating protein IV,similarity:Contains 1 C-type lectin domain.,tissue specificity:Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentialy expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.,

Gene Name: REG4

Protein Name: Regenerating islet-derived protein 4

Gen-ID: 83998

UniProt: Q9BYZ8