RASGRP3 Antikörper (AA 90-170)

Produktnummer ABIN8124241

Der Kaninchen Polyklonal anti-RASGRP3 Antikörper (ABIN8124241) detektiert spezifisch RASGRP3 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für RASGRP3 Antikörper (AA 90-170) (ABIN8124241)

Target: RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASGRP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RASGRP3 Antikörper

Bindungsspezifität: AA 90-170

Verwendungszweck: GRP3 Antibody

Spezifität: GRP3 Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 90-170

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu RASGRP3

Target: RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))

Andere Bezeichnung: GRP3

Hintergrund:

Background: RAS guanyl releasing protein 3(RASGRP3) Homo sapiens Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008],

Gene Name: RASGRP3 GRP3 KIAA0846

Protein Name: Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1)

Gen-ID: 25780

UniProt: Q8IV61