RAP1GAP Antikörper (AA 460-540)

Produktnummer ABIN8124232

Der Kaninchen Polyklonal anti-RAP1GAP Antikörper (ABIN8124232) detektiert spezifisch RAP1GAP in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für RAP1GAP Antikörper (AA 460-540) (ABIN8124232)

Target: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAP1GAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-RAP1GAP Antikörper

Bindungsspezifität: AA 460-540

Verwendungszweck: Rap1GAP Antibody

Spezifität: Rap1GAP Polyclonal Antibody detects endogenous levels of Rap1GAP protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Rap1GAP . at AA range: 460-540

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu RAP1GAP

Target: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Andere Bezeichnung: Rap1GAP

Hintergrund:

Synonyms: RAP1GAP, KIAA0474, RAP1GA1, Rap1 GTPase-activating protein 1, Rap1GAP, Rap1GAP1

Background: RAP1 GTPase activating protein(RAP1GAP) Homo sapiens This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Aug 2011],

Gene Name: RAP1GAP

Protein Name: Rap1 GTPase-activating protein 1

Gen-ID: 5909

UniProt: P47736