Proteasome alpha3 (AA 190-270) Antikörper

Produktnummer ABIN8124041

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Proteasome alpha3 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Proteasome alpha3 (AA 190-270) Antikörper (ABIN8124041)

Target: Proteasome alpha3

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: AA 190-270

Verwendungszweck: Proteasome α3 Antibody

Spezifität: This antibody detects endogenous levels of Human,Mouse,Rat Proteasome α3

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Proteasome alpha3 AA range: 190-270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Antigendetails

Target: Proteasome alpha3

Hintergrund:

Synonyms: Proteasome subunit alpha type-3 (EC 3.4.25.1, Macropain subunit C8, Multicatalytic endopeptidase complex subunit C8, Proteasome component C8)

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Gene Name: PSMA3 HC8 PSC8

Protein Name: Proteasome α3

Gen-ID: 5684

UniProt: P25788