PHC3 Antikörper (AA 720-800)
Kurzübersicht für PHC3 Antikörper (AA 720-800) (ABIN8123853)
Target
Alle PHC3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 720-800
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Verwendungszweck
- PHC3 Antibody
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Spezifität
- PHC3 Polyclonal Antibody detects endogenous levels of protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from human protein . at AA range: 720-800
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000 ELISA 1:5000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- PHC3 (Polyhomeotic Homolog 3 (PHC3))
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Andere Bezeichnung
- PHC3
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Hintergrund
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Background: function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FCS-type zinc finger.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110, BMI1/PCGF4, CBX2/M33, CBX4/PC2, CBX8/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2/RING2.,
Gene Name: PHC3 EDR3 PH3
Protein Name: Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3)
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Gen-ID
- 80012
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UniProt
- Q8NDX5
Target
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