PPARA Antikörper (pSer21)

Produktnummer ABIN8123671

Der Kaninchen Polyklonal anti-PPARA Antikörper (ABIN8123671) detektiert spezifisch PPARA in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PPARA Antikörper (pSer21) (ABIN8123671)

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PPARA Antikörper

Bindungsspezifität: pSer21

Verwendungszweck: PPAR α (Phospho Ser21) Antibody

Spezifität: This antibody detects endogenous levels of Human PPAR α (Phospho Ser21)

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human PPAR alpha (Phospho Ser21)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PPARA

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Andere Bezeichnung: PPAR alpha

Hintergrund:

Synonyms: Peroxisome proliferator-activated receptor alpha (PPAR-alpha, Nuclear receptor subfamily 1 group C member 1)

Background: function:Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.,online information:Peroxisome proliferator-activated receptor entry,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13.,tissue specificity:Skeletal muscle, liver, heart and kidney.,

Gene Name: PPARA NR1C1 PPAR

Protein Name: PPAR α (Phospho Ser21)

Gen-ID: 5465

UniProt: Q07869

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C