Peroxiredoxin 1 Antikörper

Produktnummer ABIN8123664

Der Kaninchen Monoklonal anti-Peroxiredoxin 1 Antikörper wird verwendet zum Nachweis von Peroxiredoxin 1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA, IF und IP.

Kurzübersicht für Peroxiredoxin 1 Antikörper (ABIN8123664)

Target: Peroxiredoxin 1 (PRDX1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Peroxiredoxin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: AB1770

Produktdetails anti-Peroxiredoxin 1 Antikörper

Verwendungszweck: Peroxiredoxin 1 Rabbit mAb

Spezifität: This antibody detects endogenous levels of Peroxiredoxin 1 protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Peroxiredoxin 1

Target: Peroxiredoxin 1 (PRDX1)

Andere Bezeichnung: Peroxiredoxin 1

Hintergrund:

Synonyms: PRDX1, PAGA, PAGB, TDPX2, Peroxiredoxin-1, Natural killer cell-enhancing factor A, NKEF-A, Proliferation-associated gene protein, PAG, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2

Background: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011],

Gene Name: PRDX1

Protein Name: Peroxiredoxin 1

Gen-ID: 5052

UniProt: Q06830

Pathways: p53 Signalweg, EGFR Signaling Pathway, CXCR4-mediated Signaling Events