PGC Antikörper (pSer15)

Produktnummer ABIN8123630

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PGC in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Pflanzen.

Kurzübersicht für PGC Antikörper (pSer15) (ABIN8123630)

Target: PGC (Pepsinogen C (PGC))

Reaktivität: Pflanzen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-PGC Antikörper

Bindungsspezifität: pSer15

Verwendungszweck: PEPC (Phospho Ser15) Antibody

Spezifität: The antibody detects endogenous PEPC (Phospho Ser15) protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic Peptide of PEPC (Phospho Ser15)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PGC

Target: PGC (Pepsinogen C (PGC))

Andere Bezeichnung: PEPC

Hintergrund:

Synonyms: PGC, Gastricsin, Pepsinogen C

Background: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],

Gene Name: PGC

Protein Name: Gastricsin

Gen-ID: 5225

UniProt: P20142