P-Cadherin Antikörper

Produktnummer ABIN8123547

Der Maus Monoklonal anti-P-Cadherin Antikörper wird verwendet zum Nachweis von P-Cadherin in Proben von Human. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für P-Cadherin Antikörper (ABIN8123547)

Target: P-Cadherin (CDH3)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser P-Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Klon: AB1019

Produktdetails anti-P-Cadherin Antikörper

Verwendungszweck: P-cadherin mouse mAb

Spezifität: This antibody detects endogenous levels of P-cadherin protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 450-550 of the human P-cadherin protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:500-1:2000 | IHC-P, 1:50-1:200 | IF, 1:100-400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu P-Cadherin

Target: P-Cadherin (CDH3)

Andere Bezeichnung: P-cadherin

Hintergrund:

Synonyms: Cadherin-3 (Placental cadherin) (P-cadherin)

Background: cadherin 3(CDH3) Homo sapiens This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],

Gene Name: CADH3

Protein Name: P-cadherin

Gen-ID: 1001

UniProt: P22223