Osteocalcin Antikörper

Produktnummer ABIN8123531

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Osteocalcin in IHC, WB, ELISA, IP und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für Osteocalcin Antikörper (ABIN8123531)

Target: Osteocalcin (BGLAP)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Osteocalcin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Klon: AB2210

Produktdetails anti-Osteocalcin Antikörper

Verwendungszweck: Osteocalcin Rabbit mAb

Spezifität: This antibody detects endogenous levels of Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein) protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:100-1:500 | IHC, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Osteocalcin

Target: Osteocalcin (BGLAP)

Andere Bezeichnung: Osteocalcin

Hintergrund:

Synonyms: Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)

Background: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1) , but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015],

Gene Name: BGLAP

Protein Name: Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)

Gen-ID: 632

UniProt: P02818